COMPUTATIONAL SCIENTIST

Expert in Computer Science X Biology | Interested in Global Issues

Synthetic control of yeast culture growth rates (ongoing)

I am finishing a project started as a postdoc in the Klavins Lab at UW with Orlando de Lange and Alberto Carignano that we are about to publish. We engineered yeast to induce growth arrest using a number of genes/inducers that we then characterized. We then used it in a cool application. I work both …

Design of Languages for Systems and Synthetic Biology

Context We propose to encompass context-dependent genomic information and mathematical models in a logical and structured fashion through the use of attribute grammars. Attribute Grammars (AG) provide means to compute a mathematical model (possibly  encoding phenotypic traits) from a genetic construct. AGs are a framework for biological Domain Specifi c Languages (DSLs) that, unlike current formalisms …

Research on Language and Biology

The theory: Formal language and Genetic This is related to the work I have done at Peccoud’s synthetic biology lab from 2008 to 2013: Formal languages and DNA molecules Design of Languages for Systems and Synthetic Biology Biological Languages to Design Natural Genomes [Slides] Formal languages to map Genotype to Phenotype in Natural Genomes. Application: …

Information Biosecurity: context

Preventing bioterrorism requires innovative solutionsspecific to the nature of the threat. Biotechnology is not like nuclear technology. Soon, tens of thousands of laboratories worldwide will be operating in a multi-billion-dollar industry. Even students working in small laboratories will be able to carry out gene manipulation. The approach to fighting the abuse of biotechnology for terrorist purposes …

Generative Art and Computational Creativity

So pumped !! https://www.kadenze.com/courses/generative-art-and-computational-creativity-i/info

Practical Predictive Analytics: Models and Methods

from https://www.xkcd.com/882/   Really good course at: https://www.coursera.org/learn/predictive-analytics/home/welcome

Synthetic Biology Behemoth Aims to Police Its Own Industry

IEEE Spectrum July, 3rd 2018 by Elie Dolgin. https://spectrum.ieee.org/the-human-os/biomedical/ethics/synthetic-biology-behemoth-aims-to-police-its-own-industry These algorithmic and machine-learning approaches are what’s needed for biosecurity tools in the industry to move beyond simply matching sequences against known problematic strings of genetic code, says Laura Adam. Adam is cofounder of Ebiosec, a data management platform for synthetic biology, and the developer of GenoTHREAT, an open-source screening tool.

Embroidery: structures found in the natural world

2015 embroidery thread wall installation Wangaratta Art Gallery Permanent Collection http://meredithwoolnough.com.au/#/typologies/

Sisyphus – The Kinetic Art Table

https://www.kickstarter.com/projects/1199521315/sisyphus-the-kinet More on The art of motion control