Adam, L., Kozar, M., Letort, G., Mirat, O., Srivastava, A., Stewart, T., Wilson, M.L., Peccoud, J. (2011). Strengths and limitations of the federal guidance on synthetic DNA. Nature Biotechnology.
GenoTHREAT is now open source (find it on Source Forge). The press release: BLACKSBURG, Va., March 21, 2011 – A software package designed to minimize the potential risks of synthetic biology for the nation’s defense and security is now available to the gene synthesis industry and synthetic biology community in an open-source format. Virginia Tech …
Description at http://2010.igem.org/Team:VT-ENSIMAG/Genothreat Paper Adam, L., Kozar, M., Letort, G., Mirat, O., Srivastava, A., Stewart, T., Wilson, M.L., Peccoud, J. (2011). Strengths and limitations of the federal guidance on synthetic DNA. Nature Biotechnology. Code https://sourceforge.net/projects/genoguard/
http://www.sbolstandard.org/a/sbolstandard.org/sbol/community/meetings/synbiodex_group_meeting_vbi_1_7_2011
Authors Mandy L Wilson, Russell Hertzberg, Laura Adam, Jean Peccoud Publication date 2011/1/1 Book Methods in enzymology Volume 498 Pages 173-188 GenoCAD is an open source web-based system that provides a streamlined, rule-driven process for designing genetic sequences. GenoCAD provides a graphical interface that allows users to design sequences consistent with formalized design strategies specific …
International Conference on Synthetic Biology at Evry, France, December 15-16, 2010. (invited talk+poster)
The iGEM team was invited by the FBI to present their work to 30 representatives of 15 government agencies. And we visited the FBI headquarters!
The iGEM team already got results! Their project on GenoTHREAT is to be pursued: NSF awarded $1,000,000 to further develop the sequence screening software. More details: http://www.nsf.gov/awardsearch/showAward.do?AwardNumber=1060776
The team of students I am advising for iGEM 2010, VT-ENSIMAG biosecurity, is featured in this press release. They are working on implementing and characterizing the federal guidance on synthetic genomics and on building a corresponding software called GenoTHREAT. Learn more in BioTechniques and on Genomeweb.
Authors Yizhi Cai, Matthew W Lux, Laura Adam, Jean Peccoud Publication date 2009/10/9 Journal PLoS computational biology Volume5 Issue10 Pages e1000529 Abstract Recognizing that certain biological functions can be associated with specific DNA sequences has led various fields of biology to adopt the notion of the genetic part. This concept provides a finer level of granularity than the …