Authors Mandy L Wilson, Sakiko Okumoto, Laura Adam, Jean Peccoud Publication date 2013/11/8 Journal Bioinformatics Volume30 Issue2 Pages 251-257 Abstract Motivation: Expression vectors used in different biotechnology applications are designed with domain-specific rules. For instance, promoters, origins of replication or homologous recombination sites are host-specific. Similarly, chromosomal integration or viral delivery of an expression cassette imposes specific …
Adam, L., Kozar, M., Letort, G., Mirat, O., Srivastava, A., Stewart, T., Wilson, M.L., Peccoud, J. (2011). Strengths and limitations of the federal guidance on synthetic DNA. Nature Biotechnology.
GenoTHREAT is now open source (find it on Source Forge). The press release: BLACKSBURG, Va., March 21, 2011 – A software package designed to minimize the potential risks of synthetic biology for the nation’s defense and security is now available to the gene synthesis industry and synthetic biology community in an open-source format. Virginia Tech …
Description at http://2010.igem.org/Team:VT-ENSIMAG/Genothreat Paper Adam, L., Kozar, M., Letort, G., Mirat, O., Srivastava, A., Stewart, T., Wilson, M.L., Peccoud, J. (2011). Strengths and limitations of the federal guidance on synthetic DNA. Nature Biotechnology. Code https://sourceforge.net/projects/genoguard/
Authors Mandy L Wilson, Russell Hertzberg, Laura Adam, Jean Peccoud Publication date 2011/1/1 Book Methods in enzymology Volume 498 Pages 173-188 GenoCAD is an open source web-based system that provides a streamlined, rule-driven process for designing genetic sequences. GenoCAD provides a graphical interface that allows users to design sequences consistent with formalized design strategies specific …
The iGEM team already got results! Their project on GenoTHREAT is to be pursued: NSF awarded $1,000,000 to further develop the sequence screening software. More details: http://www.nsf.gov/awardsearch/showAward.do?AwardNumber=1060776
Authors Yizhi Cai, Matthew W Lux, Laura Adam, Jean Peccoud Publication date 2009/10/9 Journal PLoS computational biology Volume5 Issue10 Pages e1000529 Abstract Recognizing that certain biological functions can be associated with specific DNA sequences has led various fields of biology to adopt the notion of the genetic part. This concept provides a finer level of granularity than the …